Diabetes Care, Vol 11, Issue 2 116-118, Copyright © 1988 by American Diabetes Association
Effect of hematocrit concentration on blood glucose value determined on Glucometer II
PB Barreau and JE Buttery
Department of Clinical Chemistry, Queen Elizabeth Hospital, Woodville, Australia.
Nineteen patient blood samples each with modified hematocrit concentrations
of approximately 20, 30, 40, 50, and 60%, were assayed for their glucose
concentration by the Glucometer II. Blood removal from the test strip was
by the one- and two-blot techniques. The reference method was the Yellow
Springs Instruments (YSI) blood glucose analyzer. Glucometer II results
were falsely high for the single blot (13-59%, mean 33%) and double blot
(12-41%, mean 19%) at 20% hematocrit and falsely low at 60% hematocrit for
the single blot (22-44%, mean 37%) and the double blot (26-49%, mean 43%).
At 40-50% hematocrit, Glucometer II and YSI results agreed only for the
one-blot technique.