Diabetes Care, Vol 16, Issue 10 1325-1330, Copyright © 1993 by American Diabetes Association

ARTICLES

Prevalence of microalbuminuria in older-onset diabetes

R Klein, BE Klein and SE Moss
University of Wisconsin, Department of Ophthalmology, Madison.

OBJECTIVE--To examine the prevalence of microalbuminuria and the relationships of microalbuminuria to blood pressure and other risk factors. RESEARCH DESIGN AND METHODS--Individuals diagnosed with diabetes at > or = 30 yr of age either taking insulin (n = 435) or not taking insulin (n = 363), who were participants in the population-based Wisconsin Epidemiologic Study of Diabetic Retinopathy, were examined during 1984-1986. Random urine samples were collected and an agglutination inhibition test was used to determine the presence of microalbuminuria, which is defined as > or = 0.03 g/L but < 0.3 g/L. RESULTS--The frequency of microalbuminuria was 29.2% in those individuals taking insulin and 22.0% in those not taking insulin. Microalbuminuria was significantly associated with the male sex, older age, higher systolic blood pressure, higher GHb, use of insulin, higher recent alcohol consumption, and a history of cardiovascular disease. CONCLUSIONS--These findings suggest a relationship between controllable risk factors, blood pressure and GHb, and microalbuminuria in older-onset diabetic individuals.
CiteULike    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				W. Palmas, T. G. Pickering, J. Teresi, J. E. Schwartz, L. Field, R. S. Weinstock, and S. Shea Telemedicine Home Blood Pressure Measurements and Progression of Albuminuria in Elderly People With Diabetes Hypertension, May 1, 2008; 51(5): 1282 - 1288. [Abstract] [Full Text] [PDF]

				R. Unnikrishnan, M. Rema, R. Pradeepa, M. Deepa, C. S. Shanthirani, R. Deepa, and V. Mohan Prevalence and Risk Factors of Diabetic Nephropathy in an Urban South Indian Population: The Chennai Urban Rural Epidemiology Study (CURES 45) Diabetes Care, August 1, 2007; 30(8): 2019 - 2024. [Abstract] [Full Text] [PDF]

				P. A. McCullough, C. T. Jurkovitz, P. E. Pergola, J. B. McGill, W. W. Brown, A. J. Collins, S.-C. Chen, S. Li, A. Singh, K. C. Norris, et al. Independent Components of Chronic Kidney Disease as a Cardiovascular Risk State: Results From the Kidney Early Evaluation Program (KEEP) Arch Intern Med, June 11, 2007; 167(11): 1122 - 1129. [Abstract] [Full Text] [PDF]

				W. Palmas, A. Moran, T. Pickering, J. P. Eimicke, J. Teresi, J. E. Schwartz, L. Field, R. S. Weinstock, and S. Shea Ambulatory Pulse Pressure and Progression of Urinary Albumin Excretion in Older Patients With Type 2 Diabetes Mellitus Hypertension, August 1, 2006; 48(2): 301 - 308. [Abstract] [Full Text] [PDF]

				P. Palatini, T. J. Wang, J. C. Evans, J. B. Meigs, N. Rifai, C. S. Fox, R. B. D'Agostino, D. Levy, and R. S. Vasan Letter Regarding Article by Wang et al, "Low-Grade Albuminuria and the Risks of Hypertension and Blood Pressure Progression" * Response Circulation, August 30, 2005; 112(9): e121 - e121. [Full Text] [PDF]

				Prevention or Delay of Type 2 Diabetes Diabetes Care, January 1, 2004; 27(90001): s47 - 47. [Full Text] [PDF]

				The Prevention or Delay of Type 2 Diabetes Diabetes Care, January 1, 2003; 26(90001): s62 - 69. [Full Text] [PDF]

				The Prevention or Delay of Type 2 Diabetes Clin. Diabetes, July 1, 2002; 20(3): 109 - 116. [Full Text] [PDF]

				The Prevention or Delay of Type 2 Diabetes Diabetes Spectr, July 1, 2002; 15(3): 147 - 157. [Full Text] [PDF]

				J. B. Meigs, R. B. D'Agostino Sr., D. M. Nathan, N. Rifai, and P. W.F. Wilson Longitudinal Association of Glycemia and Microalbuminuria: The Framingham Offspring Study Diabetes Care, June 1, 2002; 25(6): 977 - 983. [Abstract] [Full Text] [PDF]

				American Diabetes Association The Prevention or Delay of Type 2 Diabetes Diabetes Care, April 1, 2002; 25(4): 742 - 749. [Full Text] [PDF]

				A Varghese, R Deepa, M Rema, and V Mohan Prevalence of microalbuminuria in type 2 diabetes mellitus at a diabetes centre in southern India Postgrad. Med. J., June 1, 2001; 77(908): 399 - 402. [Abstract] [Full Text]

				A Melville, R Richardson, D Lister-Sharp, and A McIntosh Complications of diabetes: renal disease and promotion of self-management Qual. Saf. Health Care, December 1, 2000; 9(4): 257 - 263. [Full Text]

				E. K. Hoogeveen, P. J. Kostense, P. E. D. Eysink, B. C. P. Polak, P. J. Beks, C. Jakobs, J. M. Dekker, G. Nijpels, R. J. Heine, L. M. Bouter, et al. Hyperhomocysteinemia Is Associated With the Presence of Retinopathy in Type 2 Diabetes Mellitus: The Hoorn Study Arch Intern Med, October 23, 2000; 160(19): 2984 - 2990. [Abstract] [Full Text] [PDF]

				C. T. Valmadrid, R. Klein, S. E. Moss, and B. E. K. Klein The Risk of Cardiovascular Disease Mortality Associated With Microalbuminuria and Gross Proteinuria in Persons With Older-Onset Diabetes Mellitus Arch Intern Med, April 24, 2000; 160(8): 1093 - 1100. [Abstract] [Full Text] [PDF]

				M Bouma, J. Dekker, J. van Eijk, F. Schellevis, D. Kriegsman, and R. Heine Metabolic control and morbidity of Type 2 diabetic patients in a general practice network Fam. Pract., August 1, 1999; 16(4): 402 - 406. [Abstract] [Full Text] [PDF]

				The CDC Diabetes Cost-Effectiveness Study Group The Cost-effectiveness of Screening for Type 2 Diabetes JAMA, November 25, 1998; 280(20): 1757 - 1763. [Abstract] [Full Text] [PDF]