Diabetes Care
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kane, L. A.
Right arrow Articles by Service, F. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kane, L. A.
Right arrow Articles by Service, F. J.
Social Bookmarking
Add to CiteULike   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Diabetes Care, Vol 16, Issue 9 1298-1300, Copyright © 1993 by American Diabetes Association

ARTICLES

Insulinoma in a patient with NIDDM

LA Kane, CS Grant, TB Nippoldt and FJ Service
Department of Internal Medicine, Mayo Medical School, Rochester, MN 55905.

OBJECTIVE--To confirm insulinoma as the cause of hypoglycemia in a patient with NIDDM and determine the frequency of the co-occurrence of these two conditions. RESEARCH DESIGN AND METHODS--The patient underwent an in-hospital prolonged fast (< or = 72 h), according to standard protocol, and an ultrasound examination of the pancreas. All cases of histologically confirmed insulinoma at this institution over the period of 1927-1992 were reviewed to determine the prevalence of pre-existent diabetes mellitus. RESULTS--After 10 h of fasting, plasma glucose was low (1.89 mM); plasma insulin (258 pM) and C-peptide (1.39 nM) were elevated in the absence of sulfonylurea in the plasma. An insulinoma detected by ultrasonography was removed surgically with subsequent reoccurrence of insulin-requiring diabetes. Among 313 cases of insulinoma confirmed at this institution, this patient is the only one with pre-existent diabetes mellitus. CONCLUSIONS--Insulinoma occurs extraordinarily rarely in patients with pre-existing NIDDM.
Add to CiteULike CiteULike   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Journal of the American Animal Hospital AssociationHome page
E. R. Bryson, E. C.R. Snead, C. McMillan, L. MacDougall, and A. L. Allen
Insulinoma in a Dog With Pre-existing Insulin-Dependent Diabetes Mellitus
J. Am. Anim. Hosp. Assoc., January 1, 2007; 43(1): 65 - 69.
[Abstract] [Full Text] [PDF]

Home page
 Clin. DiabetesHome page
P. Sapountzi, G. Charnogursky, M. A. Emanuele, D. Murphy, F. Nabhan, and N. V. Emanuele
Case Study: Diagnosis of Insulinoma Using Continuous Glucose Monitoring System in a Patient With Diabetes
Clin. Diabetes, July 1, 2005; 23(3): 140 - 143.
[Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
E. Arioglu, N. A. Gottlieb, C. A. Koch, J. L. Doppman, N. J. Grey, and P. Gorden
Natural History of a Proinsulin-Secreting Insulinoma: From Symptomatic Hypoglycemia to Clinical Diabetes
J. Clin. Endocrinol. Metab., October 1, 2000; 85(10): 3628 - 3630.
[Full Text]

Home page
 NEJMHome page
F.J. Service
Hypoglycemic Disorders
N. Engl. J. Med., April 27, 1995; 332(17): 1144 - 1152.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1993 by the American Diabetes Association.