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Diabetes Care, Vol 18, Issue 10 1373-1375, Copyright © 1995 by American Diabetes Association
Ginseng therapy in non-insulin-dependent diabetic patients
EA Sotaniemi, E Haapakoski and A Rautio
Department of Internal Medicine, University of Oulu, Finland.
OBJECTIVE: To investigate the effect of ginseng on newly diagnosed
non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN
AND METHODS: In this double-blind placebo-controlled study, 36 NIDDM
patients were treated for 8 weeks with ginseng (100 or 200 mg) or placebo.
Efficacy was evaluated with psychophysical tests and measurements of
glucose balance, serum lipids, aminoterminalpropeptide (PIIINP)
concentration, and body weight. RESULTS: Ginseng therapy elevated mood,
improved psychophysical performance, and reduced fasting blood glucose
(FBG) and body weight. The 200-mg dose of ginseng improved glycated
hemoglobin, serum PIIINP, and physical activity. Placebo reduced body
weight and altered the serum lipid profile but did not alter FBG.
CONCLUSIONS: Ginseng may be a useful therapeutic adjunct in the management
of NIDDM.

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Copyright © 1995 by the American Diabetes Association.
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