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Diabetes Care, Vol 18, Issue 2 206-209, Copyright © 1995 by American Diabetes Association

ARTICLES

Effects of personality on metabolic control in IDDM patients

A Orlandini, MR Pastore, A Fossati, S Clerici, A Sergi, A Balini, MA Parlangeli, C Maffei, A Secchi and G Pozza
Neuropsychic Sciences Department, H. San Raffaele Scientific Institute, Milan, Italy.

OBJECTIVE--The aim of this study was to evaluate the relationship between poor metabolic control and maladaptive personality traits (according to the Diagnostic and Statistical Manual of Mental Disorders, Third Edition-Revised) in an adult-onset insulin-dependent diabetes mellitus sample group (n = 77). RESEARCH DESIGN AND METHODS--Metabolic control was evaluated through glycosylated hemoglobin (HbA1c). Personality traits were assessed with the Personality Diagnostic Questionnaire-Revised, a self-administered questionnaire. Residual pancreatic secretion (fasting serum C-peptide) was also evaluated. RESULTS--Principal components analysis revealed three personality profiles: "withdrawn-suspicious" (P1), "dramatic-dependent" (P2), and "aggressive-irresponsible" (P3). Multiple linear regression analysis showed that C-peptide levels and P2 personality profiles were significant and independent predictors of HbA1c plasma levels: P2 predicted high HbA1c values and C-peptide predicted low HbA1c levels. CONCLUSIONS--These data suggest that a P2 personality profile is a significant predictor of poor metabolic control.
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