Diabetes Care
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Waldecker, B.
Right arrow Articles by Tillmanns, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Waldecker, B.
Right arrow Articles by Tillmanns, H.
Social Bookmarking
Add to CiteULike   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Diabetes Care, Vol 22, Issue 11 1832-1838, Copyright © 1999 by American Diabetes Association

ARTICLES

Type 2 diabetes and acute myocardial infarction. Angiographic findings and results of an invasive therapeutic approach in type 2 diabetic versus nondiabetic patients

B Waldecker, W Waas, W Haberbosch, R Voss, MK Steen-Muller, A Hiddessen, R Bretzel and H Tillmanns
Department of Medicine, Justus-Liebig University, Giessen, Germany. bernd.waldecker@innere.med.uni-giessen.de

OBJECTIVE: Mortality in diabetic patients with acute myocardial infarction (MI) is high. The significance of the pretreatment coronary status in type 2 diabetic patients with acute MI, as well as the effect of mechanical revascularization using percutaneous transluminal coronary angioplasty (PTCA), has not been established. RESEARCH DESIGN AND METHODS: All patients with type 2 diabetes and acute MI (n = 54) were prospectively enrolled into a study of immediate coronary angiography to guide PTCA of the occluded infarct vessel. Hospital and long-term course were assessed and compared with an unselected control group of nondiabetic patients (n = 358) who were enrolled in the same study. RESULTS: Angiography showed that sites of occlusion and acute coronary flow were similar in both groups. Multivessel disease and shock were more common in type 2 diabetic versus nondiabetic patients: 69 vs. 51% and 21 vs. 10% (P < 0.02), respectively. Direct PTCA was successful in > 90% in both groups. Mortality after 30 days was 13% in type 2 diabetic patients versus 5% in patients without diabetes (P < 0.04). Left ventricular (LV) ejection fraction before discharge was lower in diabetic patients (48 +/- 17 vs. 55 +/- 15%, P < 0.05). Mortality 1 year after discharge was 11 vs. 4% in diabetic versus nondiabetic patients (P < 0.02). Multivariate analysis identified type 2 diabetes as an independent risk factor for acute, but not for late, mortality. CONCLUSIONS: Direct PTCA is safe and effective in type 2 diabetic patients with acute MI. Mortality after 30 days in unselected diabetic patients is < 15% with this approach. Advanced disease and shock contribute to an increased mortality in type 2 diabetic patients with acute MI versus nondiabetic patients.
Add to CiteULike CiteULike   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 QJMHome page
J.R. Timmer, J.P. Ottervanger, H.J.G. Bilo, J.H.E. Dambrink, K. Miedema, J.C.A. Hoorntje, and F. Zijlstra
Prognostic value of admission glucose and glycosylated haemoglobin levels in acute coronary syndromes
QJM, April 1, 2006; 99(4): 237 - 243.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
E. Bonnefoy, P. G. Steg, S. Chabaud, P.-Y. Dubien, F. Lapostolle, F. Boudet, J.-M. Lacroute, F. Dissait, G. Vanzetto, A. Leizorowicz, et al.
Is primary angioplasty more effective than prehospital fibrinolysis in diabetics with acute myocardial infarction? Data from the CAPTIM randomized clinical trial
Eur. Heart J., September 1, 2005; 26(17): 1712 - 1718.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
K P Morgan, A Kapur, and K J Beatt
Anatomy of coronary disease in diabetic patients: an explanation for poorer outcomes after percutaneous coronary intervention and potential target for intervention
Heart, July 1, 2004; 90(7): 732 - 738.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
J. R Timmer, J. P. Ottervanger, K. Thomas, J. C.A Hoorntje, M.-J. de Boer, H. Suryapranata, F. Zijlstra, and on behalf of the Zwolle myocardial infarction stud
Long-term, cause-specific mortality after myocardial infarction in diabetes
Eur. Heart J., June 1, 2004; 25(11): 926 - 931.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
D. A. Alter, Y. Khaykin, P. C. Austin, J. V. Tu, and J. E. Hux
Processes and Outcomes of Care for Diabetic Acute Myocardial Infarction Patients in Ontario: Do physicians undertreat?
Diabetes Care, May 1, 2003; 26(5): 1427 - 1434.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
L F Hsu, K H Mak, K W Lau, L L Sim, C Chan, T H Koh, S C Chuah, R Kam, Z P Ding, W S Teo, et al.
Clinical outcomes of patients with diabetes mellitus and acute myocardial infarction treated with primary angioplasty or fibrinolysis
Heart, September 1, 2002; 88(3): 260 - 265.
[Abstract] [Full Text] [PDF]

Home page
 British Journal of Diabetes & Vascular DiseaseHome page
E. Erdmann
Cardiovascular events in patients with type 2 diabetes
The British Journal of Diabetes & Vascular Disease, January 1, 2002; 2(1_suppl): S4 - S8.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1999 by the American Diabetes Association.