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Diabetes Care, Vol 7, Issue 3 280-284, Copyright © 1984 by American Diabetes Association

ARTICLES

Pregnancy following renal transplantation in a patient with insulin-dependent diabetes mellitus

F Vinicor, A Golichowski, R Filo, EJ Smith and D Maxwell

Renal transplantation and peritoneal or hemodialysis are therapeutic options increasingly available to diabetic patients with uremia. We report a patient with insulin-dependent diabetes mellitus (IDDM) and advanced retinopathy and nephropathy who had three pregnancies. Her first pregnancy resulted in a living female with Pierre-Robin syndrome and arthrogryposis. The second pregnancy, 8 mo post-kidney transplantation, necessitated a therapeutic abortion for an anencephalic fetus. Her third pregnancy, 22 mo after kidney transplantation, was associated with intensive diabetes management and resulted in delivery by cesarean section of a healthy boy. Renal and retinal function remained stable during both her second and third pregnancies. As more patients with IDDM achieve fertility post-renal transplantation, aggressive principles of diabetes regulation need to be expanded to include consideration of the interaction of the post-kidney-transplant state and diabetes mellitus during pregnancy.
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Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1984 by the American Diabetes Association.