Diabetes Care, Vol 8, Issue 2 125-128, Copyright © 1985 by American Diabetes Association
The prevalence of symptomatic, diabetic neuropathy in an insulin-treated population
AJ Boulton, G Knight, J Drury and JD Ward
The prevalence of symptomatic sensorimotor polyneuropathy has been
determined in a population of 382 insulin-treated diabetic subjects aged
15-59 yr. Forty-one subjects (10.7%) were found to have diabetic
neuropathy, according to strict diagnostic criteria that required the
presence of symptoms and signs of nerve dysfunction in the absence of
peripheral vascular disease. There was a significant correlation between
glycosylated hemoglobin levels and motor conduction velocity in the median
and peroneal nerves in all subjects. This finding further emphasizes the
importance of metabolic factors related to hyperglycemia in the impaired
nerve function seen in diabetic patients.