Diabetes Care, Vol 8, Issue 4 343-348, Copyright © 1985 by American Diabetes Association
Prospective evaluation of HDL cholesterol changes after diet and physical conditioning programs for patients with type II diabetes mellitus
RM Kaplan, DK Wilson, SL Hartwell, KL Merino and JP Wallace
High-density lipoprotein (HDL) cholesterol is known to be low in patients
with diabetes mellitus. Low HDL levels are correlated with premature
cardiovascular mortality in several major epidemiologic studies and many
investigators believe increases in HDL cholesterol may reduce the risk of
coronary heart disease. We evaluated dietary and exercise interventions in
relation to HDL cholesterol in patients with type II diabetes mellitus.
Sixty-five volunteers were randomly assigned to one of four experimental
conditions: diet, exercise, diet plus exercise, or education control. Three
months after entering the program, those exposed to the dietary
intervention had significant increases in HDL cholesterol. HDL increases
for the other two treatment groups did not differ significantly from the
education control.